K/U: Knowledge and Understanding T/I: Thinking and Investigation C: Communication A: Application
For each question, select the best answer from the four alternatives.
1. If analysis of the double-stranded DNA in an organism reveals that 30 % of the nitrogenous bases are adenine, which statement is true? (6.1) T/I (a) 15 % must be thymine. (b) The combined percentage of adenine and thymine must be 60 %. (c) 30 % must be guanine. (d) The combined percentage of guanine and cytosine must be 60 %.
2. On which part of a DNA molecule does the negative charge reside? (6.1) K/U (a) phosphate groups (b) sugar molecules (c) nitrogenous bases (d) all of the above
3. Which describes the possible effect of a genetic mutation? (6.2) K/U (a) harmful (b) beneficial (c) neutral (d) any of the above
4. What is the term for a chromosomal mutation in which gametes inherit too many or too few chromosomes? (6.2) K/U (a) translocation (b) non-disjunction (c) frameshift defect (d) autosomal error
5. Which of the following is another name for a transposon? (6.2) K/U (a) regulator gene (b) jumping gene (c) promoter gene (d) frameshift gene
6. About how many genes are there in the human genome? (6.3) K/U (a) 200 (b) 2000 (c) 20 000 (d) 200 000
7. Which of the following is the preferred term for "junk" DNA? (6.3) K/U (a) mutated DNA (b) transposed DNA (c) interpolated DNA (d) non-coding DNA
8. Which term describes the role of plasmids in genetic engineering? (6.4) K/U (a) vector (b) transposon (c) mutagen (d) chemical scissors
9. Which function was restored in guinea pigs, using experimental gene therapy in 2005? (6.5) K/U (a) hearing (b) vision (c) muscular coordination (d) red blood cell count
Indicate whether each statement is true or false. If you think the statement is false, rewrite it to make it true.
10. The component of nucleotides that contains nitrogen is deoxyribose. (6.1) K/U
11. If a scientist wished to determine the pattern in which the atoms of a pure substance are arranged, he might use microarray technology. (6.1, 6.2) K/U
12. Damage to a cell's DNA caused by ultraviolet radiation could cause a spontaneous mutation. (6.2) K/U
13. Antibiotics were discovered when mould was observed to kill bacteria in laboratory cultures. (6.2) K/U
14. The National DNA Data Bank in Canada stores the DNA of endangered species. (6.3) K/U
15. Recombinant DNA is created by connecting nucleotide sequences that would never be found together in nature. (6.4) K/U
16. Bt corn is genetically engineered to be more drought resistant than normal corn. (6.4) K/U
17. Muscular Dystrophy Canada believes that stem cell treatment holds the most promise for curing Duchenne muscular dystrophy. (6.5) K/U
18. Figure 1 (next page) shows a diagram of a single DNA strand. Match the terms below to the labels in the diagram. (6.1) K/U (a) phosphate group (b) pentose sugar molecule (c) thymine (d) guanine (e) adenine (f) cytosine
Print Page 259
Key
K/U: Knowledge and Understanding T/I: Thinking and Investigation C: Communication A: Application
Match the scientist(s) on the left with the most appropriate discovery or theory on the right.
19. (a) Alfred Hershey and Martha Chase (b) James Watson and Francis Crick (c) Rosalind Franklin and Maurice Wilkins (d) Phoebus Levene (e) Joachim Hammerling (f) Friedrich Miescher
(i) A material in the nuclei of algae cells directs regeneration. (ii) Nuclein (now called DNA) is present in cell nuclei. (iii) Viral DNA alone can make bacteria produce new viruses. (iv) DNA is a double helix held together by weak forces between bases. (v) DNA has three main chemical components. (vi) DNA has a helical structure. (6.1) K/U
REVIEW
Knowledge
Key
K/U: Knowledge and Understanding
T/I: Thinking and Investigation
C: Communication
A: Application
For each question, select the best answer from the four alternatives.
1. If analysis of the double-stranded DNA in an organism reveals that 30 % of the nitrogenous bases are adenine, which statement is true? (6.1) T/I
(a) 15 % must be thymine.
(b) The combined percentage of adenine and thymine must be 60 %.
(c) 30 % must be guanine.
(d) The combined percentage of guanine and cytosine must be 60 %.
2. On which part of a DNA molecule does the negative charge reside? (6.1) K/U
(a) phosphate groups
(b) sugar molecules
(c) nitrogenous bases
(d) all of the above
3. Which describes the possible effect of a genetic mutation? (6.2) K/U
(a) harmful
(b) beneficial
(c) neutral
(d) any of the above
4. What is the term for a chromosomal mutation in which gametes inherit too many or too few chromosomes? (6.2) K/U
(a) translocation
(b) non-disjunction
(c) frameshift defect
(d) autosomal error
5. Which of the following is another name for a transposon? (6.2) K/U
(a) regulator gene
(b) jumping gene
(c) promoter gene
(d) frameshift gene
6. About how many genes are there in the human genome? (6.3) K/U
(a) 200
(b) 2000
(c) 20 000
(d) 200 000
7. Which of the following is the preferred term for "junk" DNA? (6.3) K/U
(a) mutated DNA
(b) transposed DNA
(c) interpolated DNA
(d) non-coding DNA
8. Which term describes the role of plasmids in genetic engineering? (6.4) K/U
(a) vector
(b) transposon
(c) mutagen
(d) chemical scissors
9. Which function was restored in guinea pigs, using experimental gene therapy in 2005? (6.5) K/U
(a) hearing
(b) vision
(c) muscular coordination
(d) red blood cell count
Indicate whether each statement is true or false. If you think the statement is false, rewrite it to make it true.
10. The component of nucleotides that contains nitrogen is deoxyribose. (6.1) K/U
11. If a scientist wished to determine the pattern in which the atoms of a pure substance are arranged, he might use microarray technology. (6.1, 6.2) K/U
12. Damage to a cell's DNA caused by ultraviolet radiation could cause a spontaneous mutation. (6.2) K/U
13. Antibiotics were discovered when mould was observed to kill bacteria in laboratory cultures. (6.2) K/U
14. The National DNA Data Bank in Canada stores the DNA of endangered species. (6.3) K/U
15. Recombinant DNA is created by connecting nucleotide sequences that would never be found together in nature. (6.4) K/U
16. Bt corn is genetically engineered to be more drought resistant than normal corn. (6.4) K/U
17. Muscular Dystrophy Canada believes that stem cell treatment holds the most promise for curing Duchenne muscular dystrophy. (6.5) K/U
18. Figure 1 (next page) shows a diagram of a single DNA strand. Match the terms below to the labels in the diagram. (6.1) K/U
(a) phosphate group
(b) pentose sugar molecule
(c) thymine
(d) guanine
(e) adenine
(f) cytosine
Print Page 259
Key
K/U: Knowledge and Understanding
T/I: Thinking and Investigation
C: Communication
A: Application
Match the scientist(s) on the left with the most appropriate discovery or theory on the right.
19.
(a) Alfred Hershey and Martha Chase
(b) James Watson and Francis Crick
(c) Rosalind Franklin and Maurice Wilkins
(d) Phoebus Levene
(e) Joachim Hammerling
(f) Friedrich Miescher
(i) A material in the nuclei of algae cells directs regeneration.
(ii) Nuclein (now called DNA) is present in cell nuclei.
(iii) Viral DNA alone can make bacteria produce new viruses.
(iv) DNA is a double helix held together by weak forces between bases.
(v) DNA has three main chemical components.
(vi) DNA has a helical structure. (6.1) K/U